Unlocking Joint Youth: How Inhibiting 15-PGDH Could Redefine Osteoarthritis Treatment
Unlocking Joint Youth: How Inhibiting 15-PGDH Could Redefine Osteoarthritis Treatment Osteoarthritis (OA) silently erodes joint cartilage, turning daily movement into pain for millions. Current options—painkillers, therapy, or knee/hip replacement—manage symptoms but fail to restore lost tissue. A 2025 breakthrough from Stanford changes this narrative by targeting 15-hydroxyprostaglandin dehydrogenase (15-PGDH), an enzyme dubbed a “gerozyme” for […]
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